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KMID : 0363220180560040269
Korean Journal of Dermatology
2018 Volume.56 No. 4 p.269 ~ p.272
A Case of Sexual Enhancer Induced Fixed Drug Eruption
Lee Soo-Kyung

Kim Dong-Joo
Suh Joong-Heon
Kim Myoung-Shin
Lee Un-Ha
Abstract
Fixed drug eruption is a commonly reported mucocutaneous drug eruption. A 61-year-old male presented to our clinic with a complaint of an itchy round erythematous patch on the left hand dorsum with myalgia. On taking medical history, the patient correlated the episode with the intake of an oral sexual enhancer that he had obtained over the counter. We found the medicine contained tadalafil and sildenafil in combination with herbal ingredients. A short course of oral corticosteroid therapy resulted in the complete resolution of the lesion leaving residual hyperpigmentation of the skin involved. Various sexual enhancers with fancy names and attractive packaging are available without requiring a doctor¡¯s prescription. Most contain phosphodiesterase-5 inhibitors in various concentrations, often with herbal additions. These drugs are used erratically by the lay public, and often produce side effects. Herein, we report a case of fixed drug rash related to a sexual enhancer, which we believe to be the first report in Korea.
KEYWORD
Fixed drug eruption, Phosphodiesterase 5 inhibitors, Sexual enhancer, Sildenafil, Tadalafil
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